NWEH and OneAdvanced Collaborate to Transform Clinical Trial Delivery

We are proud to be working in strategic collaboration with OneAdvanced to transform how clinical trials are delivered by securely integrating real-world primary care data directly into research workflows.

This collaboration represents a step-change in how research can be delivered across the NHS.

By connecting clinical correspondence managed within OneAdvanced’s, Docman system to our trial delivery platform ConneXon, we are creating a more connected research ecosystem, one that brings clinical trials closer to routine care, improves safety oversight, and enables richer real-world evidence generation.

Docman manages the flow of essential clinical communications across care settings, including, referrals, discharge summaries, diagnostic and laboratory results, and outpatient and specialist letters. These records form a longitudinal narrative of real clinical decision-making, information that has historically been fragmented or delayed in research environments.

By enabling controlled consented access to this correspondence, NWEH can now gain near-real-time visibility into patient care events outside formal study visits. This significantly improves data completeness, accuracy, and timeliness across trial delivery.

Shared commitment to innovation

This alignment reflects a shared commitment to responsible innovation, safe data access, and strengthening the role of digital infrastructure in advancing UK clinical research. Nicole Kayode, VP of Product for Health & Care at OneAdvanced, explained:

“When NorthWest EHealth reached out about the opportunity to support clinical trials, it was really aligned to the direction of travel we were thinking of going.”

Jo Verity, Head of Clinical Operations at NWEH, said: “As soon as I was aware that OneAdvanced had the capacity to share patient data—their discharge summaries, the medical letters shared between general practice and secondary care, it opened so many more doors for us to deliver research in different models. It allows us to really decentralise delivery models for clinical research.”

“It felt like a bit of a no-brainer for us to join forces and find a way to integrate the clinical record directly into the research process.” added Kayode.

By working together, the capabilities of Docman and ConneXon will significantly reduce the administrative burden on nursing staff and GP practices involved in studies by removing the need to manually chase clinical documentation. It enables remote oversight of clinically meaningful events, provides greater visibility of patient journeys between visits, reduces reliance on hospital-centric research sites, and allows earlier awareness of changes that may affect eligibility or safety.

Improving access to research participation

The integration also strengthens NWEH’s mission to make clinical research more accessible and inclusive.

Rachel Downham, Chief Commercial Officer at NWEH, noted: “People who take part don’t have the burden of having to be at a specific study centre every week, which may previously have been an inhibitor. This includes primary caregivers, people with kids to get to school, and workplaces to be at. It’s ensuring we can bring in a population that historically may not have taken part, so we have equity in real-world trials.”

By embedding research into routine care settings, this approach supports participation from broader and more representative patient populations.

Stronger safety oversight

Access to near-real-time clinical correspondence enhances pharmacovigilance and safety monitoring by enabling earlier detection of safety-relevant events, confirmation of diagnoses and treatment changes, and faster reconciliation between routine care and trial records.

This also supports more complete safety narratives for regulatory review. For sponsors, this translates into higher-quality datasets, improved endpoint validation, fewer protocol deviations, and smoother trial execution across complex care pathways.

Looking ahead

Our first major clinical trial incorporating OneAdvanced’s technology is already underway, marking an important milestone in advancing data-enabled research.

This creates opportunities for longitudinal patient journey analysis, enhanced real-world evidence platforms, remote pre-screening through integration with FARSITE, and expansion to additional data sources and research-active practices.

Together with OneAdvanced, we are building infrastructure that brings research and care closer together, benefiting patients, clinicians, sponsors, and the wider health system.

For more information click here to visit OneAdvanced.